David H. Broide, MB, ChB

David H. Broide, MB, ChB
Professor of Medicine
Research Training Program Director

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Dr. Broide received his MB, ChB (Medicine) from the University of Cape Town, South Africa. He later completed his post-doctoral studies in allergy/immunology at the Unversity of California, San Diego. He is board certified in internal medicine and allergy/immunology.

Research Interests

  • Mechanisms of allergic inflammation and asthma
  • Airway hyperreactivity, airway inflammation, mucus expression, and airway remodeling
  • Immunohistology and image analysis quantitation of eosinophils, mast cells, T cells, and macrophages in the lung
  • Eosinophils and mast cells in vitro and in vivo

Clinic Focus

  • Asthma
  • Sinus allergy
  • Allergen immunotherapy
  • Anaphylaxis
Clinical Profile and Appointments

Clinic Practice Locations

Perlman Medical Offices

Selected Publications

  1. Le AV, Cho JY, Miller M, McElwain S, Golgotiu K, Broide DH. Inhibition of allergen induced airway remodeling in Smad3 deficient mice. J Immunol 178: 7310-7316 (2007).
  2. Hayashi T, Mo JH, Gong X, Rossetto C, Jang A, Beck I, Elliot GI, Kufareva I, Abagyan R, Broide DH, Lee J, Raz E. 3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis. Proc Natl Acad Sci USA 104: 18619-24 (2007).
  3. Fong CH, Bebien M, Sisierlaurent A Newbauer R, Hussell T, Broide D, Karin M, Lawrence T. An anti-inflammatory role for IKKbeta through the inhibition of “classical” macrophage activation. J Exp Med 205: 1269-76 (2008).
  4. Miller M, Cho JY, Pham A, Ramsdell J, Broide DH. Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in COPD. J Immunol (2009) 182:684-91.
  5. Song DJ, Cho JY, Lee SY, Miller M, Rosenthal P, Soroosh P, Croft M, Zhang M, Varki A, Broide DH. Anti-Siglec-F antibody reduces allergen induced eosinophilic inflammation and airway remodeling. J Immunol. 183:5333-41 (2009).

Additional Broide Publications via PubMed