David L. Boyle, BA

Boyle, David L.

David L. Boyle, BA
Professor of Medicine

Director of Laboratories,
Clinical and Translational Research Institute Health Sciences

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Mr. David Boyle received his BA at the University of California, San Diego, in biochemistry and cell biology. 

Professional Experience

  • 1982-1993, Staff Research Associate
  • University of California, San Diego
  • 1993-1996, Associate Scientist
  • Gensia, Inc. San Diego, California
  • 1996 -Present, Associate Project Immunologist
  • University of California, San Diego
  • 2001-Present, Director, Biomarker Laboratory
  • University of California, San Diego

Research Interests

  • Pathogenesis of rheumatoid arthritis
  • Role of p38 in animal models of arthritis
  • In vitro studies of MAPK signaling and p38 signaling

Selected Publications

  1. Buch MH, DL Boyle, S Rosengren, B Saleem, R Reece, L Rhodes, A Radjenovic, A English, H Tang, G Vratsanos, P O’Connor, GS Firestein, P Emery. Mode of action of abatacept in rheumatoid arthritis patients having failed TNF blockade: a histological, gene expression and dynamic MRI pilot study. In press Ann Rheum Dis 68:1220-1227 (2009).
  2. Chen Y, Khanna S, Goodyear CS, Park YB, Raz E, Thiel S, Grönwall C, Vas J, Boyle DL, Corr M, Kono DH, Silverman GJ. Regulation of Dendritic Cells and Macrophages by an Anti-Apoptotic Cell Natural Antibody that Suppresses TLR Responses and Inhibits Inflammatory Arthritis. J Immunol. 183:1346-1359 (2009).
  3. Herbst KL, AD Coviello, A Chang, DL Boyle. Lipomatosis-associated inflammation and excess collagen may contribute to lower relative resting energy expenditure in women with adiposis dolorosa. doi: 10.1038/ijo.2009.119 (2009).
  4. Chao J, C Wu, B Sun, MK Hose, A Quan, TH Hughes, D Boyle, KC Kalunian. Inflammatory Characteristics on Ultrasound Predict Poorer Longterm Response to Intraarticular Corticosteroid Injections in Knee Osteoarthritis. J Rheum. 37:650-655 (2010).
  5. Rosengren S, Corr M, Boyle DL. PDGF and TGF-beta synergistically potentiate inflammatory mediator synthesis Arthritis Res Ther 12:R65 (2010) PMID: 20380722.

Additional Boyle Publications via PubMed